Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disease, and pain is its common symptom that severely impairs patients' quality of life. The pain mechanism of HS is complex, characterized by a combination of nociceptive, neuropathic and nociceptive plasticity features. Its management should be based on the biopsychosocial model: for acute pain, intralesional triamcinolone acetonide injection, non-steroidal anti-inflammatory drugs (NSAIDs) and topical preparations can be administered; for chronic pain, multimodal therapy is recommended, such as duloxetine combined with pregabalin. Individualized regimens are required for pediatric, pregnant and elderly patients. In addition, physical therapy, surgical intervention, wound care and psychological support are also indispensable. This paper summarizes the pathogenesis, clinical characteristics and assessment methods of pain in HS, aiming to provide a reference for optimizing individualized treatment strategies and comprehensively improving patients' quality of life.

Key words: hidradenitis suppurativa, pain management, chronic pain, acute pain