中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (11): 651-654.doi: 10.12144/zgmfskin201911651

• 论著 • 上一篇    下一篇

反射式共聚焦显微镜监测玫瑰痤疮治疗前后毛囊蠕形螨数量变化

陈蕾  高峰  李金勇  郭新云  于维恒   

  1. 潍坊市皮肤病防治所，山东潍坊，261061
  • 出版日期:2019-11-15 发布日期:2019-11-20
  • 通讯作者: 陈蕾，E-mail：cl_cp@126.com

Detection of demodex mites with reflectance confocal microscopy in the patients with rosacea before and after treatment

CHEN Lei, GAO Feng，LI Jinyong，GUO Xinyun，YU Weiheng   

  1. Weifang Institude of Dermotology, Weifang 261061, China
  • Online:2019-11-15 Published:2019-11-20
  • Contact: CHEN Lei, E-mail: cl_cp@126.com

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摘要： 目的：利用反射式共聚焦显微镜（RCM）观察玫瑰痤疮患者治疗前后毛囊蠕形螨数量的变化。方法：收集我科50例玫瑰痤疮患者，治疗前后分别用RCM对其面部特定部位进行毛囊蠕形螨的检测。结果：50例患者均检出毛囊蠕形螨，5 mm×5 mm扫描面积下，治疗前后毛囊蠕形螨总数分别为91.60±25.57和42.95±10.20，受累毛囊数量分别为33.38±8.10和21.05±4.98，差异均具有统计学意义（均P<0.05）。结论：随着治疗及临床症状的改善，玫瑰痤疮患者毛囊蠕形螨感染数量下降。

关键词: 反射式共聚焦显微镜, 玫瑰痤疮, 毛囊蠕形螨

Abstract: Objective: To detect the qauntity change of demodex mites with RCM in the patients with rosacea before and after treatment. Methods: Fifty patients with facial rosacea were collected and the number of demodex mites in the patients were detected with RCM before and after therapy. Results: Demodex mites were found in all 50 patients. The average numbers of demodex mites in 5 mm×5 mm scanning area were 91.60±25.57 and 42.95±10.20, and the average hair follicles affected were 33.38±8.10 and 21.05±4.98 before and after treatment, with significant differences (Ps<0.05). Conclusion: The number of demodex mites in the patients with rosacea decreases with the effective therapy.

Key words: reflectance confocal microscopy, rosacea, demodex mites