中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (5): 305-307.doi: 10.12144/zgmfskin202105305

• 临床研究 • 上一篇    下一篇

56例角化棘皮瘤临床分析

吴倩1,张志勇2   

  1. 1华北理工大学研究生学院，河北唐山，063000；
    2唐山市工人医院病理科，河北唐山，063000
  • 出版日期:2021-05-15 发布日期:2021-04-29
  • 通讯作者: 张志勇，E-mail: 1073810505@qq.com

Analysis of clinical features in 56 patients with keratoacanthoma

WU Qian1, ZHANG Zhiyong2   

  1. 1 The Graduate School of North China University of Science and Technology, Tangshan 063000, China; 
    2 Department of Pathology, Tangshan Gongren Hospital, Tangshan 063000, China
  • Online:2021-05-15 Published:2021-04-29
  • Contact: ZHANG Zhiyong, E-mail: 1073810505@qq.com

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摘要： 回顾性分析我院2015年1月至2020年1月角化棘皮瘤患者的临床资料。 共收集56例角化棘皮瘤患者，其中男34例，女22例，平均发病年龄(60.73±14.29)岁，发病部位：面部33例(58.9%)，四肢远端11例(19.6%)，手部4例(7.1%)，头皮3例(5.4%)，臀部2例(3.6%)，颈部1例(1.8%)，腰部1例(1.8%)及阴阜1例(1.8%)。其中54例单发，2例泛发。49例(87.5%)表现为大小不等的圆顶形、质稍硬的隆起型肿物。56例中7例伴发早期鳞癌，1例具有HPV病毒感染史，1例具有家族史。所有患者均予手术切除皮损，20例患者获得随访，3例复发（其中1例死亡）。

关键词: 角化棘皮瘤, 临床表现, 病理分析

Abstract: The data of the patients with keratoacanthoma from January 2015 to January 2020 in our hospital were analyzed. Fifty six patients with keratoacanthoma were collected including 34 males and 22 females with an average age of 60.73±14.29 years. There were 33 lesions on the face (58.9%), 11 on the limbs (19.6%),  4 on fingers (7.1%), 3 on scalp (5.4%), 2 on buttocks (3.6%), 1 on neck (1.8%), 1 on waist (1.8%) and 1 on mons pubis (1.8%). The lesions were solitary in 54 patients and diffuse in 2 patients. The dome shaped and slightly hard protuberant tumors of different sizes presented in 49 cases (87.5%). Of 56 patients, 7 were accompanied with cancer, 1 was positive for HPV, and 1 had family history. All patients had received surgery treatment and 20 were followed up successfully. The lesions reappeared in 3 cases including 1 death. 

Key words: keratoacanthoma, clinical symptoms, pathological analysis