中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (2): 122-124.doi: 10.12144/zgmfskin202302122

• 病例报告 • 上一篇    下一篇

多重耐药性金黄色葡萄球菌致面部假性上皮瘤样肉芽肿一例

邱云,居哈尔·米吉提,布瓦杰尔·亚克亚,张德志,于世荣,康晓静   

  1. 新疆维吾尔自治区人民医院皮肤性病科，新疆皮肤病临床医学研究中心，新疆皮肤病研究重点实验室（XJYS1707），乌鲁木齐，830001
  • 出版日期:2023-02-15 发布日期:2022-12-28

Pseudoepitheliomatous granuloma of the face caused by multi resistant Staphylococcus aureus: a case report

QIU Yun, Juhaer·mijiti, Buwajieer·yakeya, ZHANG Dezhi, YU Shirong, KANG Xiaojing   

  1. Department of Dermatology and Venereology, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center For Dermatologic Diseases, Xinjiang Key Laboratory of Dermatology Research（XJYS1707）, Urumchi 830001, China
  • Online:2023-02-15 Published:2022-12-28

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摘要： 患者，男，31岁。右侧面部出现红色斑块1个月，逐渐形成肿块改变。发病前有被羊角擦伤史。皮损组织病理示：表皮渗出结痂，表皮呈假上皮瘤样增生、棘层呈灶状水肿，真皮乳头高度水肿，真皮层较密集以淋巴细胞、中性粒细胞、嗜酸粒细胞及组织细胞和多核巨细胞为主的炎细胞浸润。皮损组织真菌培养、分枝杆菌快速培养和抗酸杆菌染色均阴性。局部分泌物细菌培养示：金黄色葡萄球菌（MSSA）。诊断：面部慢性感染性肉芽肿（多重耐药性金黄色葡萄球菌引起）。予口服莫西沙星治疗7天后痊愈。

关键词: 感染性肉芽肿, 金黄色葡萄球菌, 假上皮瘤样肉芽肿

Abstract: A 31-year-old male presented with red plaques on the right side of the face for one month, gradually forming mass changes. The patient had been scratched by the horn of sheep before the onset of the disease. The pathology showed the epidermis exuded and scabbed, the epidermis showed pseudoepithelioma like hyperplasia, the Acanthous layer showed focal edema, the dermal papilla was highly edematous, and the dermis was densely infiltrated by inflammatory cells mainly composed of lymphocytes, neutrophils, eosinophils, histiocytes and multinuclear giant cells. Fungal culture, Mycobacterium fast culture and acid fast bacilli staining were all negative. The culture of local secretion bacteria indicated that Staphylococcus aureus (MSSA). The diagnosis of chronic infectious granuloma of face (caused by multidrug-resistant Staphylococcus aureus) was made. The patient recovered after 7 days of oral moxifloxacin treatment.

Key words: infectious granuloma, Staphylococcus aureus, pseudoepitheliomatous granuloma