中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (6): 425-427.doi: 10.12144/zgmfskin202406425

• 病例报告 • 上一篇    下一篇

误诊为持久性隆起性红斑的海分枝杆菌感染一例

于越乾1,2,暴芳芳1,2,刘红1,2,张福仁1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2024-06-15 发布日期:2024-05-08

Mycobacterium marinum infection misdiagnosed as persistent erythema protuberant: a case report

YU Yueqian1,2, BAO Fangfang1,2, LIU Hong1,2, ZHANG Furen1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2024-06-15 Published:2024-05-08

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摘要： 患者,女，48岁。左膝结节16个月。患者曾在外院接受伊曲康唑及氨苯砜治疗9个月，无效。患者在我院通过皮肤组织分枝杆菌培养和定量聚合酶链反应（qPCR）测序技术诊断为海分枝杆菌感染，口服利福平和克拉霉素治疗4个月，皮损明显好转。患者从出现皮肤症状到诊断为海分枝杆菌感染的时间为16个月，提醒皮肤科临床医生应注意海分枝杆菌感染的非典型临床表现。

关键词: 海分枝杆菌感染, 持久性隆起性红斑, 误诊

Abstract: A 48-year-old female presented with nodules on the left knee for 16 months. The patient had been treated with itraconazole and dapsone in another hospital for 9 months, with ineffective. The patient was diagnosed with Mycobacterium marine infection by mycobacterium culture and quantitative polymerase chain reaction (qPCR) technique of skin tissue in our hospital. After 4 months of oral rifampicin and clarithromycin, the skin lesions were significantly improved. The time from the onset of skin symptoms to the diagnosis of mycobacterium marine infection was 16 months, which reminds dermatologists should be aware of the atypical clinical manifestations of Mycobacterium marinum infection.

Key words: Mycobacterium marinum infection, erythema elevatum diutinum, misdiagnose