中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (12): 795-796.doi: 10.12144/zgmfskin202112795

• 病例报告 • 上一篇    下一篇

氨苯砜治疗持久性隆起性红斑一例

常雯茜1,2,周桂芝2,刘永霞2,刘红2,张福仁2   

  1. 1潍坊医学院，山东潍坊，261053；
    2山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2021-12-15 发布日期:2021-09-29
  • 通讯作者: 张福仁，E-mail: zhangfuren@hotmail.com

Dapsone in the treatment of erythema elevatum diutinum: a case report

CHANG Wenqian1,2, ZHOU Guizhi2, LIU Yongxia2, LIU Hong2, ZHANG Furen2   

  1. 1 Weifang Medical University, Weifang 261053, China; 2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2021-12-15 Published:2021-09-29
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

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摘要： 患者，男，78岁。躯干、四肢多发紫红色结节、斑块伴疼痛3年。组织病理示:表皮间水肿，真皮浅中层弥漫性中性粒细胞浸润，血管壁界限不清，纤维组织增生。诊断为持久性隆起性红斑。治疗：氨苯砜100 mg每日一次口服，外用卤米松乳膏和夫西地酸乳膏，4个月后皮损明显好转。

关键词: 持久性隆起性红斑, 氨苯砜

Abstract: A 78-year-old male presented with multiple purplish red nodules and plaques on the trunk and limbs with pain for 3 years. Histopathological examination showed epidermal edema and diffuse infiltration of neutrophilic in the superficial and mid-dermis, unclear vessel wall and fibrous proliferation. The diagnosis of erythema elevatum diutinum was made. The patient was treated with oral dapsone 100 mg once a day, topical halometasone cream and topical fusidic acid cream. The lesions were significantly improved after four-month follow-up.

Key words: erythema elevatum diutinum, dapsone