中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (10): 747-749.doi: 10.12144/zgmfskin202510747

• 病例报告 • 上一篇    下一篇

卡氏枝孢瓶霉致着色芽生菌病一例

杨小琦1，2,李紫阁1，2,刘永霞1，2,杨宝琦1，2,暴芳芳1，2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2025-10-15 发布日期:2025-09-29

Chromoblastomycosis caused by Cladophialophora carrionii: a case report

YANG Xiaoqi1，2, LI Zige1，2, LIU Yongxia1，2, YANG Baoqi1，2, BAO Fangfang1，2   

  1. 1 Dermatology Hospital of Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2025-10-15 Published:2025-09-29

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摘要： 患者，男，66岁。右手腕部一黄豆大斑块2年，逐渐扩大，无明显痒痛等不适，曾被误诊为瘢痕疙瘩。就诊我院后行真菌培养见暗色丝状菌落生长，光镜下可见树枝状菌丝和串珠样分生孢子簇。核糖体DNA（rDNA）内转录间隔区测序确定为卡氏枝孢瓶霉，予伊曲康唑200 mg，每日一次，治疗6个月后斑块基本消退。

关键词: 着色芽生菌病, 卡氏枝孢瓶霉

Abstract: A 66-year-old male patient presented with a soybean-sized plaque on his right wrist for 2 years, which gradually enlarged without obvious symptoms such as itching or pain. It was once misdiagnosed as keloid. After visiting our hospital, fungal culture showed the growth of dark filamentous colonies. Through sequencing analysis of the internal transcribed spacer (ITS) region of ribosomal DNA (rDNA), it was identified as Cladophialophora carrionii. The patient was given itraconazole 200 mg once daily, and the plaque basically subsided after 6 months of treatment.

Key words: chromoblastomycosis, Cladophialophora carrionii