中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (1): 55-58.doi: 10.12144/zgmfskin202601055

• 病例报告 • 上一篇    下一篇

度普利尤单抗治疗太藤丘疹红皮病一例

周钟莲,肖易,黄莹雪,粟娟,陈明亮,张谧   

  1. 中南大学湘雅医院皮肤科，湖南长沙，410008
  • 出版日期:2026-01-15 发布日期:2026-01-16

Dupilumab in the treatment of papuloerythroderma of Ofuji: a case report

ZHOU Zhonglian, XIAO Yi, HUANG Yingxue, SU Juan, CHEN Mingliang, ZHANG Mi   

  1. Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China
  • Online:2026-01-15 Published:2026-01-16

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摘要： 太藤丘疹红皮病（papuloerythroderma of Ofuji，PEO）是一种罕见的皮肤病, 主要临床表现为红棕色扁平丘疹，相互融合，似红皮病样损害且皮肤褶皱部位不受累。目前PEO的主要治疗方式包括糖皮质激素、免疫抑制剂、维A酸类药物及补骨脂素加紫外线等,疗效欠佳。本文报道度普利尤单抗成功治疗PEO一例。

关键词: 太藤丘疹红皮病, 度普利尤单抗

Abstract: Papuloerythroderma of Ofuji (PEO) is a rare skin disorder characterized by diffuse erythroderma composed of papules coalescing into plaques with sparing of skin folds. Currently, the main therapeutic modalities for PEO include glucocorticoids, immunosuppressants, retinoids, and psoralen plus ultraviolet A (PUVA) therapy, among others, with suboptimal therapeutic efficacy. This paper reports a case of PEO successfully treated with dupilumab.

Key words: papuloerythroderma of Ofuji, dupliumab