中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (2): 119-120.doi: 10.12144/zgmfskin202602119

• 病例报告 • 上一篇    下一篇

剖宫产切口处坏疽性脓皮病一例

李文怡,唐丽英   

  1. 成都市温江区人民医院皮肤科,四川成都,611130
  • 出版日期:2026-02-15 发布日期:2026-01-28

Pyoderma gangrenosum at the cesarean section incision: a case report

LI Wenyi, TANG Liying   

  1. Chengdu Wenjiang District People's Hospital, Chengdu 611130, China
  • Online:2026-02-15 Published:2026-01-28

摘要: 患者剖宫产术后4天,切口处出现溃疡,自觉疼痛、发热。皮肤科查体:下腹部剖宫产切口处一红色溃疡、渗出、坏死。给予抗生素治疗无效。切口处细菌、真菌培养结果阴性。组织病理示表皮破坏,真皮及皮下组织大量中性粒细胞浸润。诊断:坏疽性脓皮病。治疗:静脉滴注甲泼尼龙40 mg/d,外用卤米松乳膏,溃疡逐渐缩小,5天后改为口服醋酸泼尼松20 mg/d,逐渐减量,一个月后,溃疡愈合。

关键词: 剖宫产, 手术切口, 坏疽性脓皮病

Abstract: Four days after cesarean section, the patient developed an ulcer at the incision site, accompanied by subjective pain and fever. Physical examination revealed a red ulcer with exudation and necrosis at the lower abdominal cesarean section incision. Antibiotic treatment was ineffective. Bacterial and fungal cultures of the incision site were negative. Histopathological examination showed epidermal destruction and massive neutrophilic infiltration in the dermis and subcutaneous tissue. The diagnosis of pyoderma gangrenosum was made. Methylprednisolone 40 mg/day was administered intravenously, combined with topical halometasone cream. The ulcer gradually shrank; five days later, the treatment was switched to oral prednisone acetate 20 mg,once a day, with gradual tapering. The ulcer healed completely one month later.

Key words: cesarean section, surgical incision, pyoderma gangrenosum