中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (10): 725-728.doi: 10.12144/zgmfskin202610725

• 临床研究 • 上一篇    下一篇

以喉部受累为首发症状的系统性幼年性黄色肉芽肿一例

袁延帅1，2,杨海燕2,韩林杞1，2,刘丽曼1，2,赵月华2   

  1. 1山东第二医科大学临床医学院，山东潍坊，261000；2山东第二医科大学附属医院，山东潍坊，261000
  • 出版日期:2026-10-15 发布日期:2026-10-09

Systemic juvenile xanthogranuloma presenting primarily with laryngeal involvement: a case report

YUAN Yanshuai1,2, YANG Haiyan2, HAN Linqi1,2, LIU Liman1,2, ZHAO Yuehua2   

  1. 1 School of Clinical Medicine, Shandong Second Medical University, Weifang 261000, China; 2 Affiliated Hospital of Shandong Second Medical University, Weifang 261000, China
  • Online:2026-10-15 Published:2026-10-09

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摘要： 本文报道一例以喉部受累为首发症状，后续出现眼、皮肤、肝脾等多系统受累的罕见系统性幼年性黄色肉芽肿病例。本病例根据特征性病理形态及免疫组化结果确诊，予长春地辛联合泼尼松化疗治疗，症状好转。

关键词: 系统性幼年性黄色肉芽肿, 免疫组织化学, 喉

Abstract: This paper reports a rare case of systemic juvenile xanthogranuloma (SJXG) with laryngeal involvement as the initial manifestation, followed by multi-system lesions involving the eyes, skin, liver and spleen. The diagnosis was confirmed based on characteristic pathological morphology and immunohistochemical findings, and the patient achieved symptomatic improvement after chemotherapy with vindesine combined with prednisone.

Key words: systemic juvenile xanthogranuloma, immunohistochemistry, larynx