中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (10): 623-625.

• 短篇论著 • 上一篇    下一篇

点阵激光联合复方丙酸氯倍他索治疗增生性瘢痕疗效评价

李琛1，刘科峰1，田哲娟2   

  1. 1河南大学第一附属医院，河南开封，475001 2许昌市中心医院，河南许昌，461001
  • 出版日期:2016-10-15 发布日期:2018-12-19
  • 通讯作者: 刘科峰，E-mail: liukefengys@163.com

Efficacy of ablative fractional CO2 laser combined with compound clobetasol propionate in the treatment of hypertrophic scars

LI Chen1, LIU Kefeng1, TIAN Zhejuan2   

  1. 1. The First Hospital Affiliated to Henan University, Kaifeng 475001, China; 2. Xuchang Central Hospital, Xuchang 461001, China
  • Online:2016-10-15 Published:2018-12-19
  • Contact: LIU Kefeng, E-mail: liukefengys@163.com

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摘要： 目的：评价CO2点阵激光联合复方丙酸氯倍他索软膏治疗增生性瘢痕的疗效。方法：69例增生性瘢痕患者随机分为药物组（30例）和联合组（39例）。联合组应用点阵激光，30天1次，共3次，联合复方丙酸氯倍他索软膏外用，每日1次，连用3个月。药物组患者仅外用复方丙酸氯倍他索，每天1次。结果：联合组有效率为100%，明显高于药物组的76.92%（P<0.05）。联合组不良反应发生率为7.69%，明显低于药物组的13.33%（P<0.05）。结论：CO2点阵激光联合复方丙酸氯倍他索软膏治疗增生性瘢痕明显优于单独应用复方丙酸氯倍他索。

关键词: 点阵激光, 复方丙酸氯倍他索软膏, 增生性瘢痕

Abstract: Objective: To assess the efficacy of fractional CO2 laser combined with clobetasol propionate in the treatment of hypertrophic scars. ]Methods: Sixty nine patients were randomly divided into the drug group (30 patients) and the combination group (39 patients). All the patients were topically treated with clobetasol propionate, once a day for 3 months and the patients in the combination group were treated with additional fractional CO2 laser, once every 30 days for 3 times. Results: The effective rate in the combination group was 100%, which was higher than that in the drug group (76.92%), with a significant difference (P<0.05). The adverse reaction in the combination group was 7.69%, which was lower than that in the drug group (13.33%), with a significant difference (P<0.05). Conclusion: The efficacy of fractional CO2 laser combined with clobetasol propionate ointment is more effective than clobetasol propionate ointment alone in the treatment of hypertrophic scars.

Key words: fractional laser, compound clobetasol propionate, hypertrophic scars