中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (5): 267-269.

• 论著 • 上一篇    下一篇

反射式共聚焦扫描显微镜在日光性角化病诊断中的应用

吴秀娟 向 芳 赵宗峰 邹云敏 普雄明   

  1. 新疆维吾尔自治区人民医院，乌鲁木齐 830001
  • 出版日期:2016-05-15 发布日期:2018-12-24

Application of the reflectance confocal microscopy in the diagnose of actinic keratosis

WU Xiujuan, XIANG Fang, ZHAO Zongfeng, ZOU Yunmin, PU Xiongming.   

  1. People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China
  • Online:2016-05-15 Published:2018-12-24

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摘要： 目的：明确反射式共聚焦扫描显微镜（RCM）下日光性角化病的形态学特征及在诊断日光性角化病中的应用价值。方法：对136例拟诊为日光性角化病患者进行RCM技术扫描并与常规组织病理进行比较分析。结果：136例患者RCM成像特征为棘细胞层排列紊乱及角质形成细胞异型性，与日光性角化病组织病理改变一致，符合率100%。结论：日光性角化病在RCM下具有典型特征，可作为无创诊断日光性角化病的重要依据。

关键词: 共聚焦扫描显微镜, 日光性角化病

Abstract: Objective: To determine the image features of actinic keratosis (AK) under reflectance confocal microscopy (RCM) and the application value in the diagnosis of AK. Methods: The lesions of 136 patients who were clinically suspected AK were examined with RCM and the results were compared with biopsy. Results: The characteristics of AK under RCM were disorganization of stratum spinosum and atypical keratinocytes, which were accordance with the feature of histopathology of AK. The agreement rate was 100%. Conclusions: The characteristics of AK under RCM is typical and can be used as a tool in the diagnosis of AK.

Key words: reflectance confocal microscopy, actinic keratosis