中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (8): 456-459.

• 论著 • 上一篇    下一篇

皮肤镜诊断黑素细胞痣、脂溢性角化和日光性角化与组织病理诊断的一致性

杨欣融，孙睿，袁定芬，邓辉   

  1. 上海交通大学附属上海市第六人民医院皮肤科，200233
  • 出版日期:2016-08-15 发布日期:2019-03-01
  • 通讯作者: 邓辉,E-mail: denghui_1@hotmail.com

The consistency of dermoscopy and histopathology in the diagnosis of melanocytic nevus, seborrheic keratosis and solar keratosis

YANG Xinrong, SUN Rui, YUAN Dingfen, DENG Hui   

  1. Department of Dermatology, Sixth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200233, China
  • Online:2016-08-15 Published:2019-03-01
  • Contact: DENG Hui, E-mail: denghui_1@hotmail.com

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摘要： 目的：评价皮肤镜诊断黑素细胞痣、脂溢性角化、日光性角化的准确度。方法：收集临床怀疑为黑素细胞痣、脂溢性角化和日光性角化的病例，由两位医生参照目前皮肤镜诊断标准对该三种皮肤肿瘤进行盲法独立诊断，并与组织病理结果相对照。结果：与组织病理诊断比较，(1)A、B两位医生使用皮肤镜诊断黑素细胞痣一致率（89.3%、91.2%）、灵敏度（94%、95.2%）、特异度（84.2%、86.8%）、误诊率（15.8%、13.2%）、漏诊率（6%、4.8%）。(2)A、B两位医生使用皮肤镜诊断脂溢性角化一致率（88%、91.7%）、灵敏度（91.7%、95.8%）、特异度（83.6%、86.9%）、误诊率（16.4%、13.5%）、漏诊率（8.3%、4.2%）；(3)A、B两位医生使用皮肤镜诊断日光性角化一致率（84.1%、86.4%）、灵敏度（87.5%、87.5%）、特异度（17.9%、12.5%）、误诊率（82.1%、85.7%）、漏诊率（17.9%、14.3%）。结论：皮肤镜诊断黑素细胞痣、脂溢性角化和日光性角化的结果与病理诊断结果均有较好的一致性。

关键词: 皮肤镜, 组织病理, 黑素细胞痣, 脂溢性角化, 日光性角化, 一致性

Abstract: Objective: To determine the accuracy and consistency of dermoscope in the diagnose of melanocytic nevus, seborrheic keratosis and solar keratosis. Methods: Cases from November 2013 to March 2015 which were chinical diagnosed as melanocytic nevus, seborrheic keratosis and solar keratosis were enrolled, including clinical data, clinical pictures, dermoscopic diagnosis and pathological findings. Then two doctors evalauted the dermoscopy seperately, and compared with the histopathological findings. Results: (1) For the nevus the consistencysensitivity, specificity, misdiagnosis rate,and false dismissal rate between those two evaluators were seperatively (89.3%, 91.2%), (94%, 95.2%), (84.2%, 86.8%), (15.8%, 13.2%) and (6%, 4.8%). (2) For the seborrheic keratosis, the consitency, sensitivity, sepecificity, misdiagnosis rate and false dismissal rate were (88%, 91.7%）, (91.7%, 95.8%）, (83.6%, 86.9%）, (16.4%, 13.5%) and (8.3%, 4.2%). (3) For the solar keratosis, the consistency, sensitivity, specificity, misdiagnosis rate and false dismissal rate were (84.1%, 86.4%), (87.5%, 87.5%), (17.9%, 12.5%), (82.1%, 85.7%) and (17.9%, 14.3%). Conclusion: There was a high consistency in the diagnosis of melanocytic nevus and seborrheic keratosis with demoscopy, and solar keratosis by dermoscopy.

Key words: dermoscopy, histopathology, melanocytic nevus, seborrheic keratosis, solar keratosis, consistency