中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (2): 115-117”121.

• 综述 • 上一篇    下一篇

生物制剂联合免疫抑制剂治疗银屑病研究进展

张玲玲 龚瑜 史玉玲   

  1. 同济大学附属第十人民医院皮肤科,上海,200072
  • 出版日期:2018-02-15 发布日期:2018-12-06
  • 通讯作者: 史玉玲,E-mail: shiyuling1973@tongji.edu.cn
  • 基金资助:
    国家自然科学基金(编号:81301356);上海市自然科学基金(编号:13ZR1432200,16ZR1426800);上海市科委引导项目基金(编号:134119b0700)

Update of immunosuppressor combined with biologics in the treatment of patients with psoriasis

ZHANG Lingling, GONG Yu, SHI Yuling.   

  1. Department of Dermatology, Shanghai Tenth people's Hospital of Tongji University, Shanghai 200072, China
  • Online:2018-02-15 Published:2018-12-06
  • Contact: SHI Yuling, E-mail:shiyuling1973@tongji.edu.cn

摘要: 近年研究表明生物制剂与免疫抑制剂联合应用治疗银屑病能减少生物制剂单独应用时抗抗体的产生,增加生物制剂的疗效。本文就生物制剂联合免疫抑制剂在治疗银屑病中的相互作用机制,临床疗效及安全性的研究进展进行了综述。

关键词: 生物制剂, 免疫抑制剂, 银屑病

Abstract: It has been reported recently that biologics combined with immunosuppressor can reduce the production of antidrug antibodies and improve the efficacy of biologics. The update of the clinical efficacy, safety and mechanism of biologics combined with immunosuppressor in the treatment of patients with psoriasis are reviewed in this article.

Key words: biologics, immunosuppressor, psoriasis