中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (5): 287-289.

• 短篇论著 • 上一篇    下一篇

慢性自发性荨麻疹患者血清25(OH)D和IL-25水平检测

韩钰，王娟，张亚丽，贾雪松   

  1. 石河子大学第一附属医院皮肤科 新疆维吾尔族自治区 石河子832000
  • 出版日期:2018-05-15 发布日期:2018-12-10
  • 通讯作者: 贾雪松，E-mail:jiaxs0309@sina.com??

Detection of Serum 25-hydroxyvitamin D and IL-25 in the patients with chronic spontaneous urticaria

HAN Yu , WANG Juan , ZHANG Yali, JIA Xuesong   

  1. Department of Dermatology, the First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang, 83200
  • Online:2018-05-15 Published:2018-12-10
  • Contact: JIA Xuesong, E-mail:jiaxs0309@sina.com

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摘要： 目的：检测慢性自发性荨麻疹( CSU)患者血清中25(OH) D和IL-25的水平。方法：电化学发光方法和ELISA分别检测40例CSU患者及30例健康对照血清中的25(OH)D和IL-25水平。结果：CSU组血清25(OH) D水平为(19.48±7.41) ng/ mL低于对照组的(23.23±6.43) ng/mL，（P<0.05）。CSU组血清IL-25水平 为(124.59±19.32) pg/ mL高于对照组的(107.33±14.57) pg/ mL,差异有统计学意义(P<0.05)。结论：血清25(OH)D和IL-25水平可能与CSU发病相关。

关键词: 慢性自发性荨麻疹, 25羟基维生素D, 白介素25

Abstract: Objective: To detect the levels of 25-hydroxy vitamin D and IL-25 in the patients with chronic spontaneous urticaria (CSU). Methods: The levels of 25(OH) D and IL-25 were detected by electrochemiluminescence and ELISA respectively in 40 patients and 30 healthy controls. Results: The serum levels of 25(OH) D and IL-25 in the patients were 19.48±7.41 ng/mL and 124.59±19.32 pg/mL, while the levels of 25(OH) D and IL-25 were 23.23±6.43ng/mL and 107.33±14.5 in the healthy controls, with significant differences (Ps<0.05). Conclusion: The levels of serum 25 (OH) D and IL-25 may be associated with the pathogenesis of CSU.

Key words: chronic spontaneous urticaria, 25(OH) D, IL-25