中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (3): 170-171.doi: 10.12144/zgmfskin202103170

• 病例报告 • 上一篇    下一篇

泛发性汗孔角化症合并枕部巨大鳞癌一例

乌日嘎,贺伟,李艳   

  1. 内蒙古医科大学附属医院皮肤科，内蒙古呼和浩特，010050
  • 出版日期:2021-03-15 发布日期:2021-03-03
  • 通讯作者: 李艳，E-mail: 13948318299@163.com

Generalized porokeratosis accompanied with squamous cell carcinoma: a case report

WU Riga, HE Wei, LI Yan   

  1. Department of Dermatology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
  • Online:2021-03-15 Published:2021-03-03
  • Contact: LI Yan，E-mail：13948318299@163.com

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摘要： 患者，女，46岁。全身角化性丘疹30年余，头皮破溃1年余。皮肤科情况：躯干四肢褐色斑块，部分中央萎缩；枕部可见18 cm×9 cm溃疡。枕部皮损组织病理检查示条索状异型肿瘤细胞；免疫组化示鳞癌。上肢皮损组织病理检查：多个角化不全柱。诊断：泛发性汗孔角化症合并枕部巨大鳞癌。给予放疗，效果可。

关键词: 汗孔角化症, 鳞癌

Abstract: A 46-year-old female presented with keratinized plaques all over the body for more than 30 years, and ulcer on scalp for more than 1 year. Dermatological examination showed brown plaque on the trunk and limbs, some with central atrophy, and a ulcer 18 cm×9 cm in size on the occipitalia. Histopathological examination of occipital lesion showed cord-shaped atypical cells. Immunohistochemistry indicated squamous cell carcinoma. Histopathological examination of arm showed multiple hypokeratotic columns. The diagnosis of generalized porokeratosis accompanied with squamous cell carcinoma was made. The patient was treated with radiation therapy with a good result. 

Key words: porokeratosis, squamous cell carcinoma