中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (4): 221-223.doi: 10.12144/zgmfskin202104221

• 病例报告 • 上一篇    下一篇

易误诊的二期梅毒一例

朱晶,朱麒麟,顾永   

  1. 南京医科大学附属无锡人民医院 皮肤病与性病科，江苏无锡，214000
  • 出版日期:2021-04-15 发布日期:2021-04-07
  • 通讯作者: 顾永,E-mail: 317815804@qq.com

Misdiagnosis of secondary syphilis: a case report

ZHU Jing, ZHU Qilin, GU Yong   

  1. Department of Dermatology and Venereology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214000, China
  • Online:2021-04-15 Published:2021-04-07
  • Contact: GU Yong, E-mail: 317815804@qq.com

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摘要： 患者，男，34岁。左鼻孔、阴囊起无痛性丘疹、结节2个月。皮肤科检查：左鼻孔见一枚黄豆大丘疹，阴囊根部可见一蚕豆大结节。临床诊断为肿瘤，予手术切除。术前血液常规检查示：TPPA≥1∶2560；TRUST:1∶4；TPAB-ELISA:阳性。阴囊结节活检病理示表皮突增生延长，表皮内可见角化物，真皮浅层可见包含大量浆细胞的炎细胞浸润巢，诊断为二期梅毒。

关键词: 二期梅毒, 误诊, 皮肤镜

Abstract: A 34-year-old man presented with bean-sized papules on his nostril and broad bean-size nodule on his scrotum for two months. The primary dignosis was tumor and the patient was planned to treat by surgery. The preoperative blood test showed TPPA≥1∶2560, TRUST:1∶4 and positive of TPAB-ELISA. The biopsy of his scrotal nodules revealed that epidermal process hyperplasia, keratinous material in the epidermis, a massive infiltration of plasma cells in the the upper dermis. The diagnosis of secondary syphilis was made.

Key words: secondary syphilis, misdiagnose, dermoscopy