中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (7): 441-444.doi: 10.12144/zgmfskin202107441

• 临床研究 • 上一篇    下一篇

肉芽肿性蕈样肉芽肿二例并文献复习

张朝霞,施仲香,周桂芝,杜东红,杨青,王广进,刘永霞,杨宝琦   

  1. 山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），济南,250022
  • 出版日期:2021-07-15 发布日期:2021-06-25
  • 通讯作者: 杨宝琦,E-mail: baoqiyang@126.com

Granulomatous mycosis fungoides: two cases report and literature review

ZHANG Zhaoxia, SHI Zhongxiang, ZHOU Guizhi, DU Donghong, YANG Qing, WANG Guangjin, LIU Yongxia, YANG Baoqi   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Veneorology, Shandong First Medical University, Jinan 250022, China
  • Online:2021-07-15 Published:2021-06-25
  • Contact: YANG Baoqi, E-mail: baoqiyang@126.com

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摘要： 报道2例以局部浸润性斑块为主要表现的肉芽肿性蕈样肉芽肿并复习相关文献。2例患者均表现为红斑、斑块，皮损组织病理检查见真皮内淋巴样细胞及巨细胞浸润，患者1免疫组化示CD2、CD3、CD5、CD7阳性，患者2 CD2、CD3、CD4阳性及CD68组织细胞阳性。诊断：肉芽肿性蕈样肉芽肿。患者1口服阿维A及肿块局部浅层X线照射治疗。患者2给予阿维A、UVA1照射治疗。

关键词: 蕈样肉芽肿, 肉芽肿性, 诊断, 治疗

Abstract: Two cases of granulomatous mycosis fungoides with local infiltrating plaques are reported and the literature is reviewed. The two patients presented with erythema and plaques. Histological examination showed infiltration of lymphoid cells and giant cells. Immunohistochemistry showed CD2, CD3, CD5 and CD7 were positive in the first patient, who was treated with oral acitretin A and local superficial X-ray radiotherapy, and CD2, CD3, CD4 and CD68 were positive in the second patient, who was treated with acitretin A and ultraviolet A1.

Key words: mycosis fungoides, granulomatous, diagnosis, therapy