中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (8): 608-610.doi: 10.12144/zgmfskin202308608

• 病例报告 • 上一篇    下一篇

免疫吸附联合糖皮质激素、免疫抑制剂治疗以高球蛋白血症性紫癜为主要表现的干燥综合征一例

韩畅,戴莉萍,田红军,陈新鹏,肖剑伟   

  1. 深圳市福田区风湿病专科医院风湿科，广东深圳，518040
  • 出版日期:2023-08-15 发布日期:2023-07-19

Immunoadsorption combined with glucocorticoid and immunosuppressant in the treatment of Sjogren's syndrome with hyperglobulinemic purpura as the main manifestation: a case report

HAN Chang, DAI Liping, TIAN Hongjun, CHEN Xinpeng, XIAO Jianwei   

  1. Department of Rheumatology,  Shenzhen Futian Hospital for Rheumatic Disease, Shenzhen 518040, China
  • Online:2023-08-15 Published:2023-07-19

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摘要： 患者，女，44岁。反复全身斑疹10年，加重1个月。既往经糖皮质激素、中药、维生素等治疗未见好转。唇腺组织病理活检见5个淋巴聚集灶，结合抗核抗体等相关检查诊断为干燥综合征、高球蛋白血症性紫癜、肾小管酸中毒I型可能，给予免疫吸附联合糖皮质激素、免疫抑制剂治疗后病情好转。

关键词: 免疫吸附, 干燥综合征, 高球蛋白血症性紫癜

Abstract: A 44-year-old female presented with repeated systemic macular rash for 10 years, aggravated for 1 month. And no improvement was observed after previous treatment with glucocorticoid, traditional Chinese medicine, and vitamins. According to biopsy of labial gland tissue showed 5 lymphatic aggregation dryness combined with other examination of antinuclear antibodies, the diagnosis of Sjogren's syndrome, hyperglobulinemia purpura, and suspected diagnosis of renal tubular acidosis type I was made. After immunoadsorption combined with glucocorticoid and immunosuppressant treatment, the patient was improved.

Key words: immunoadsorption, Sjogren's syndrome, hyperglobulinemia purpura