中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (12): 894-897.doi: 10.12144/zgmfskin202312894

• 病例报告 • 上一篇    下一篇

界线类偏瘤型麻风伴神经炎和难治性Ⅱ型麻风反应一例

黎静1,2,宁宁1,2,许宗严3,关杨2,4,李祥子2,4,李超2,4,薛浩泽1,2,黄俊新1,2,蔡于茂1,2   

  1. 1深圳市慢性病防治中心性病麻风病防控科，广东深圳，518020；2深圳市皮肤病防治研究所，广东深圳，518020；3深圳市福田区慢性病防治院皮肤科，广东深圳，518110；4深圳市慢性病防治中心皮肤科，广东深圳，518020
  • 出版日期:2023-12-15 发布日期:2023-11-22

Borderline lepromatous leprosy with neuritis and refractory type II leprosy reaction: a case report

LI Jing1,2, NING Ning1,2, XU Zongyan3, GUAN Yang2,4, LI Xiangzi2,4, LI Chao2,4, XUE Haoze1,2, HUANG Junxin1,2, CAI Yumao1,2   

  1. 1 Department of STD and Leprosy Control, Shenzhen Center of Chronic Disease Prevention and Control, Shenzhen 518020, China; 2 Shenzhen Institute of Dermatology, Shenzhen 518020, China; 3 Department of Dermatology , Futian District Chronic Disease Prevention Institute, Shenzhen 518110, China; 4 Department of Dermatology, Shenzhen Center of Chronic Disease Prevention and Control, Shenzhen 518020, China
  • Online:2023-12-15 Published:2023-11-22

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摘要： 本文报道一例40岁女性患者，四肢反复出现疼痛性结节红斑6年余，先后19次于外院就诊均按“结节性红斑”诊断和治疗。4年前经皮肤组织液及病理检查被确诊为界线类偏瘤型麻风（BL）伴神经炎。抗麻风治疗期间Ⅱ型麻风反应频繁发作，予以沙利度胺、泼尼松为主的抗神经炎和麻风反应治疗，目前已治疗4年余，治疗效果明显，但Ⅱ型麻风反应减药即发作。

关键词: 麻风, 界线类偏瘤型麻风, 麻风反应

Abstract: We report a 40-year-old female with recurrent painful erythema nodosum on the limbs for more than 6 years. She was diagnosed and treated according to “erythema nodosum” for 19 times in other hospitals. The patient was diagnosed as borderline metachronous leprosy (BL) with neuritis by skin tissue fluid and pathological examination four years ago. Type Ⅱ leprosy reaction occurred frequently during anti-leprosy treatment. The patient has been treated with anti-neuritis and leprosy reaction based on thalidomide and prednisone for more than 4 years, and the therapeutic effect is obvious.

Key words: leprosy, borderline lepromatous leprosy, leprosy reaction