Abstract: A 23-year-old female presented with nodule on the left labia majora for 1 year. Histopathology showed infiltration of round or polygonal cells in the dermis, which rich in fine granular cytoplasm and small round nuclei in the center，large eosinophilic bodies in cytoplasm. Immunohistochemical examination showed tumor cells S100 (+), NSE (+), CD68 (weakly positive), CK (-), Ki-67 <1%. The diagnosis of (vulvar) granulosa cell tumor was made. The lesion resection was performed. There was no recurrence after 3-month follow-up. 

Key words: vulva, granular cell tumor