China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (4): 220-224.doi: 10.12144/zgmfskin202204220

• Original Articles • Previous Articles     Next Articles

Lichen sclerosus complicated with lichen planus and morphea: a case report and literature review

LYU Jiaqi1,2, CHANG Jianmin1,2   

  1. 1 Department of Dermatology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China; 2 Graduate School of Peking Union Medical College, Beijing 100730, China
  • Online:2022-04-15 Published:2022-02-10
  • Contact: CHANG Jianmin, E-mail: changjianmin@medmail.com.cn

Abstract:  The etiology of lichen sclerosing (LS), lichen planus (LP) and morpheas is unknown. The patients with any two diseases of LS, LP and morpheas have been reported many times, but it is rare that patients suffer from LS complicated with LP and morpheas, and there are no relevant reports in China at present. Herein, we reported a case of patients with LS complicated with LP and sclerenchyma, and reviewed 7 cases who were reported abroad. Of 8 cases, 2 were males and 6 were females, the average age was (60.3±15.1) years. LS occured simultaneously with morphea, or morphea occured earlier than LS, and the pathological features of one lesion can be characterized by both lichen planus and morphea lesions. LP occured earlier or later than LS and morphea. Most patients presented with extragenital LS, generalized morphea, and classical or erosive LP.  Six cases had immune-related laboratory abnormalities and four cases were combined with other autoimmune diseases.

Key words: lichen sclerosus, lichen planus, morphea