Abstract: Skin aging primarily includes exogenous and endogenous senescence. Various physical and chemical factors principally rise exogenous aging. Endogenous aging is driven chiefly by natural aging with age. The mechanisms affiliated with natural aging are complex, involving genes, mitochondria, telomeres, hormones, and other factors. However, there is no explicit definition of the specific mechanism of natural aging. The latest research of endogenous skin aging in recent years is reviewed in this paper.

Key words: skin, aging, endogenous