China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (5): 334-337.doi: 10.12144/zgmfskin202205334

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Update of the study of endogenous skin senescence

XU Xiaoqing,CHENG Hui,YANG Sen   

  1. Department of Dermatology, First Affiliated Hospital of Anhui Medical University; Institute of Dermatology, Anhui Medical University, Heifei 230022, China
  • Online:2022-05-15 Published:2022-03-15
  • Contact: CHENG Hui, E-mail:ahmu.ch813@163.com; YANG Sen, E-mail: yang2004sen@163.com

Abstract: Skin aging primarily includes exogenous and endogenous senescence. Various physical and chemical factors principally rise exogenous aging. Endogenous aging is driven chiefly by natural aging with age. The mechanisms affiliated with natural aging are complex, involving genes, mitochondria, telomeres, hormones, and other factors. However, there is no explicit definition of the specific mechanism of natural aging. The latest research of endogenous skin aging in recent years is reviewed in this paper.

Key words: skin, aging, endogenous