China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (12): 901-907.doi: 10.12144/zgmfskin202212901

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Update of herbal extract application on androgenic alopecia prevention and treatment

ZHU Lijian, LI Hailong, ZHANG Ting, FU Hangjie, WENG Zhiwei, DING Bin   

  1. Zhejiang Chinese Medical University, College of Life Science, Hangzhou 310053, China
  • Online:2022-12-15 Published:2022-10-26

Abstract: Androgenic alopecia (AGA) is a frequent cause of hair loss. Few therapies are currently available. The application of minoxidil combined finasteride present an attenuative effect. However, some adverse effects have been also observed in clinic. Various researches suggested the beneficial effects of the herbal extracts on AGA. The pharmacological studies on these herbal extracts, which mainly included the attenuation of the androgen sensitivity, improvement of the blood circulation and nutrient supplementation, regulation of hair follicle regeneration, as well as the anti-inflammatory and antioxidant efficiencies are reviewed. This review may provide some suggestions for the further studies and the applications of these herbs on AGA treatment.

Key words: androgenic alopecia, herbal extract, pharmacology, androgen, hair follicle