Abstract: Tissue-resident memory T (TRM) cells are a newly discovered memory T cell subset. Skin TRM cells play a protective role in skin infections (such as HSV, Candida albicans, and Leishmania infections) and skin neoplastic diseases (such as melanoma and squamous cell carcinoma), and play a pathogeniq role in some autoinflammatory skin diseases. In this paper, we review the update of skin tissue-resident memory T cells and inflammatory skin diseases recurrence, especially psoriasis, vitiligo, atopic dermatitis, fixed drug eruption, alopecia areata and frontal fibrous alopecia.

Key words: TRM, psoriasis, vitiligo, atopic dermatitis, fixed drug eruption, alopecia areata, frontal fibrous alopecia