Abstract: Platelet-rich plasma (PRP) is rich in a variety of growth factors and cytokines. It can promote the proliferation and migration of melanocytes, inhibit local immune-inflammatory responses, improve cell adhesion and skin microenvironment, and thus facilitate repigmentation of lesions, showing promising application potential in the treatment of vitiligo. This review summarizes the biological basis, clinical research, potential mechanisms, and limitations of PRP in vitiligo treatment, to provide a reference for further research and clinical application of PRP in vitiligo.

Key words: platelet-rich plasma, vitiligo, melanocytes, immune regulation