Abstract: Objective: To compare the efficacy and adverse reactions of 532 nm KTP laser and 595 nm pulsed dye laser in the treatment of port wine stain. Methods: The lesions of 18 patients were divided into two areas. One area was treated with 532 nm KTP laser and another area was treated with 595 nm pulsed dye laser, once every 2~3 months for 2~4 times. The safety and efficacy were evaluated after the treatment and in 2-3 months after the treatment. Results: There was no significant difference in the cure rate between 532 nm KTP laser and 595 nm pulsed dye laser. Some patients who were resistant to pulsed dye laser treatment were also sensitive to the treatment with 532 nm KTP laser. There were less pain and less purpura in the group of 532 nm KTP laser. Only one patient in each group developed hyperpigmentation. Conclusion: 532 nm KTP laser has similar efficacy to 595 nm pulsed dye laser and relatively less adverse reactions. It can be used as an alternative treatment of port wine stain.

Key words: port-wine stains, 532 nm KTP laser, pulsed-dye laser, efficacy, adverse reaction