China Journal of Leprosy and Skin Diseases ›› 2017, Vol. 33 ›› Issue (11): 690-692,697.

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Update of immune mechanism of rosacea

LI Mingfeng, JIANG Juan.   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Online:2017-11-15 Published:2018-12-12
  • Contact: JIANG Juan, E-mail: drjjiang@vip.163.com

Abstract: The pathogenesis of rosacea includes immune responses, increasing of microorganisms and neurovascular dysfunction. Immune responses associated with rosacea include aberrant innate immune responses such as the increasing level of LL-37, KLK5 and TLR2,the activation of inflammasome and mast cell. In addition, adaptive immune mechanism is also involved in the progression of rosacea. The immune mechanism of rosacea is reviewed in this paper.

Key words: rosacea, immunity