IL-22在扁平苔藓中的表达

Abstract

Abstract: Objective: To detect the expression of interleukin-22（IL-22）in lichen planus （LP）. Methods: The expression of IL-22 in 30 LP samples and 10 normal skin samples was detected by immunohistochemisty. Results: The expression of IL-22 in lichen planus lesions mainly seen in keratinocytes of epidermal layer and the cytoplasm of infiltrating lymphocytes in superficial dermal. In the normal skin IL-22 was mainly expressed in keratinocytes near basal layer. The expression level of IL-22 was significantly higher in lesions of lichen planus than in normal skin (P<0.01). Conclusion: The expression of IL-22 may be associated with LP.

Key words: IL-22, lichen planus, keratinocytes;immunohistochemisty

ZHU Shanshan, Wang Yunlong, PANG Chuanchao. Expression of IL-22 in the lesions of lichen planus[J].China Journal of Leprosy and Skin Diseases, 2018, 34(7): 418-421.

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Expression of IL-22 in the lesions of lichen planus

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