Abstract: Pharmacological studies have shown that total glucosides of paeony (TGP) has not only the effects of anti-inflammatory and immune regulation, but also has the functions of hepatic protection, analgesia and so on. TGP is commonly used to treat some of the autoimmune diseases in clinic. As the mechanism of TGP is gradually uncovered in anti-inflammatory and immune regulatory effects, it has been increasingly applied to therapy of various immune-associated dermatoses. The update of total glucosides of paeony in treatment of the immune-associated dermatoses is reviewed in this paper.

Key words: total glucosides of paeony, immune regulation, mechanism, immune-associated dermatoses