中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (3): 151-154.doi: 10.12144/zgmfskin201903151

• 论著 • 上一篇    下一篇

A型肉毒素治疗银屑病一例并文献复习

郑林  马坚池  郑博文  田翠翠  谭国珍   

  1. 中山大学孙逸仙纪念医院皮肤科，广州，510120
  • 出版日期:2019-03-15 发布日期:2019-04-04
  • 通讯作者: 谭国珍，E-mail:13678906833@163.com

Botulinum toxin type-A in the treatment of psoriasis: a case report and literatures review

ZHENG Lin, MA Jianchi, ZHENG Bowen, TIAN Cuicui, TAN Guozhen   

  1. Department of Dermatology, Sun Yat-sen Memorial Hospital, Guangzhou 510120, China
  • Online:2019-03-15 Published:2019-04-04
  • Contact: TAN Guozhen, E-mail: 13678906833@163.com

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摘要： 有文献报道A型肉毒素治疗顽固性斑块型银屑病和反转型银屑病效果较好。本文报道A型肉毒素治疗斑块型银屑病患者一例并对相关文献进行复习。患者右小腿外侧皮损作为靶皮损（PASI=7分），注射A型肉毒素，臀部皮损（PASI=6分）为对照靶皮损，无特殊治疗。A型肉毒素注射1个月后回访，右小腿皮疹明显好转，PASI=1分；臀部对照皮损，无明显好转，PASI=5分。

关键词: A型肉毒素, 银屑病

Abstract: It was reported that Botulinum toxin type-A was effective for treating recalcitrant plaque psoriasis and inverse psoriasis . One patient with plaque psoriasis treated with Botulinum toxin type-A was reported in this paper and related literatures were reviewed. The lesions on the right calf was treated by Botulinum toxin type-A and that on the buttock was as control, with no treatment. The lesion treated by Botulinum toxin type-A improved markedly and the PASI score reduced from 7 to 1 after one month, while the control lesion did not have obvious improvement the PASI score reduced from 6 to 5. 

Key words: Botulinum toxin type-A, psoriasis