中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (4): 228-230.doi: 10.12144/zgmfskin201904228

• 短篇论著 • 上一篇    下一篇

非典型一期梅毒二例并文献复习

张园1,2,3  郑荣涛2,3  田洪青2,3   

  1. 1济南大学山东省医学科学院医学与生命科学学院,济南，250000
    2山东省皮肤病性病防治研究所,济南，250022
    3山东省皮肤病医院,济南，250022
  • 出版日期:2019-04-15 发布日期:2019-05-20
  • 通讯作者: 田洪青，E-mail: tianhq2006@126.com

Atypical primary syphilis：two cases report and literature review

ZHANG Yuan1,2,3， ZHENG Rongtao2,3， TIAN Hongqing2,3   

  1. 1. School of Medicine and Life Sciences，University of Jinan－Shandong Academy of Medical Sciences，Jinan 250000，China; 2. Shandong Provincial Institute of Dermatology and Venereology，Jinan 250022，China; 3． Shandong Provincial Hospital for Skin Diseases，Jinan 250022，China 
  • Online:2019-04-15 Published:2019-05-20
  • Contact: TIAN Hongqing, E-mail: tianhq2006@126.com

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摘要： 报道二例非典型一期梅毒并对相关文献进行复习。病例1，男，34岁。阴茎红斑、水疱10天；病例2，男，55岁。阴茎溃疡2天。两者行甲苯胺红不需加热血清实验（TRUST）、血清梅毒螺旋体颗粒凝集试验（TPPA）检测，病例1均为阳性，病例2均为阴性，两者阴茎皮损处分泌物梅毒螺旋体核酸扩增（TP-PCR）检测均阳性，诊断为一期梅毒。

关键词: 一期梅毒, 非典型

Abstract: Two patients with primary syphilis were reported and relevant literatures are reviewed. Case 1 was a 34-year-old male who presented with patch and vesicle lesions on his penis for 10 days. Case 2 was a 55-year-old male who presented with ulcer lesions on his penis for 2 days. The toluidine red unheated serum test (TRUST) and treponema pallidum particle agglutination test (TPPA) test of case 1 were positive but both were negative for case 2. Polymerase chain reactions of Treponema pallidum (TP-PCR) in penile lesion secretions were positive for both patients. The diagnosis of primary syphilis was made.

Key words: primary syphilis, atypical