中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (9): 539-541.doi: 10.12144/zgmfskin201909539

• 短篇论著 • 上一篇    下一篇

色素性痒疹10例临床分析

王岚琦  吴琼  吴依旋  鞠强   

  1. 上海交通大学医学院附属仁济医院，上海，200127
  • 出版日期:2019-09-15 发布日期:2019-09-16
  • 通讯作者: 鞠强，E-mail: qiangju@aliyun.com

Clinical analysis of 10 cases with prurigo pigmentosa

WANG Lanqi, WU Qiong, WU Yixuan, JU Qiang   

  1. Departments of Dermatology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
  • Online:2019-09-15 Published:2019-09-16
  • Contact: JU Qiang, E-mail: qiangju@aliyun.com

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摘要： 对2016年8月至2018年8月我院10例（男1例，女9例）色素性痒疹的临床资料进行回顾性分析。患者平均发病年龄26.42岁。1例早期患者，皮损表现为荨麻疹样的丘疹、斑块；5例进展期患者，皮损表现为网状分布的红色丘疹；2例恢复期患者，皮损表现为上覆痂皮的丘疹伴网状棕色斑疹；2例晚期患者，皮损仅表现为网状色素沉着。 10例患者中5例患者在发病前有饮食改变。1例合并I型糖尿病。1例患者衣物摩擦后皮损加重。1例月经前期皮损加重。6例患者检测了尿酮体，其中3例患者尿酮体升高。 10例患者确诊后给予口服米诺环素100 mg/天口服，疗程7~15天，8例患者皮损消退。

关键词: 色素性痒疹, 米诺环素

Abstract: The clinical data of 10 patients (1male and 9 females) with prurigo pigmentosa (PP) from August 2016 to August 2018 in our outpatient department was analyzed retrospectively. The average age at onset was 26.42 years old. Skin lesions were characterized by urticarial papules, plaques in one early patient, red papules with reticular distribution in 5 progressive patients, papules and reticulate macula in 2 recovered patients, reticulate hyperpigmentation in 2 advanced patients. Of 10 patients, 5 had a dietary changes history, 1 patient accompanied with type 1 diabetes mellitus. The lesion aggravated after rubbing by clothes in 1 patient and the lesion aggravated before menstruation in 1 patient. The urinary ketone bodies was detected in 6 patients and positive in 3 patients. All the patients were treated with minocycline, 100 mg a day for 7 to 15 days. The lesions subsided in 8 patients. 

Key words: prurigo pigmentosa, minocycline