中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (5): 272-274.doi: 10.12144/zgmfskin202005272

• 论著 • 上一篇    下一篇

8876例不同性别患者尖锐湿疣组织HPV基因型对比研究

曾成龙,朱继锋,朱冠男,冯婷,闫丹,赵小东,王胜春   

  1. 第四军医大学西京皮肤医院，陕西西安，710032
  • 出版日期:2020-05-15 发布日期:2020-05-28
  • 通讯作者: 朱继锋，E-mail: 24923435@qq.com

Comparison of HPV genotype in different gender among 8876 patients with condyloma acuminatum

ZENG Chenglong, ZHU Jifeng, ZHU Guannan, FENG Ting, YAN Dan, ZHAO Xiaodong, WANG Shengchun   

  1. Department of Dermatology at Xijing Hospital, Fourth Military Medical University, Xi"an 710032, China
  • Online:2020-05-15 Published:2020-05-28
  • Contact: ZHU Jifeng, E-mail: 24923435@qq.com

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摘要： 目的：分析男性和女性尖锐湿疣患者HPV基因型分布特点。方法：回顾性分析2010年9月至2019年9月我院确诊的8876例CA患者（男5717例，女3159例）HPV基因型。结果：男女患者均以20～29岁最多。女性多重感染率为47.07%，高于男性的36.85%，差异具有统计学意义（χ2=88.144，P<0.0001）。女性高危型的感染率为46.35%，高于男性的34.60%，差异具有统计学意义（χ2=120.069，P<0.0001）。结论：男性和女性CA患者HPV基因型分布特点不同，女性多重感染率和高危型HPV感染率显著高于男性。

关键词: 尖锐湿疣, 性别, HPV, 基因型

Abstract: Objective: To analyze the difference in HPV genotype between male and female. Methods:The data of 8876 patients (5717 males and 3159 females) with Condyloma acuminatum (CA) diagnosed from September 2010 to September 2019 was analyzed retrospectively. Results: Of 8876 patients, the age was from 20 to 29 years old in majority of the patients. The rates of multiple infection were 47.07% in females and 36.85% in males, with a significant difference (χ2=88.144, P<0.0001). The rate of high-risk type infection was 46.35% in females and 34.60% in males, with a  significant difference (χ2=120.069, P<0.0001). Conclusion: The HPV genotype was different between males and females. The infection rates of multiple infection and high-risk type in females were higher than in males.

Key words: condyloma acuminatum, gender, human papillomavirus, genotype