中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (2): 113-115.doi: 10.12144/zgmfskin202102113

• 综述 • 上一篇    下一篇

角蛋白在皮肤老化过程中的研究进展

张琪,王再兴,杨森   

  1. 安徽医科大学第一附属医院皮肤性病科,安徽医科大学皮肤病研究所,合肥,230032
  • 出版日期:2021-02-15 发布日期:2021-02-03
  • 通讯作者: 杨森,E-mail: yangsen@medmail.com.cn

Progress of keratin in skin aging

ZHANG Qi, WANG Zaixing, YANG Sen   

  1. Institute of Dermatology, Department of Dermatovenereology, First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
  • Online:2021-02-15 Published:2021-02-03
  • Contact: YANG Sen, E-mail: yangsen@medmail.com.cn

摘要: 角蛋白是上皮细胞中由中间丝形成的一种蛋白质,迄今为止已发现的人类角蛋白有54种,包括28种I型和26种II型角蛋白。研究角蛋白在皮肤老化中的表达,对研究预防和延缓皮肤衰老提供新的思路和指导意义。本文就近年来角蛋白在皮肤老化过程中的研究进展进行综述。

关键词: 角蛋白, 光老化, 皮肤屏障

Abstract: Keratin is a protein formed by intermediate filaments in epithelial cells. To date, 54 species of human keratin have been found, including 28 type I and 26 type II keratins. Study on the expression of keratin in skin aging can provide new ideas and guidance for the preventing and delaying skin aging. The update of keratin in skin aging is presented in this paper.

Key words: keratin, photoaging, skin barrier