中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (5): 355-359.doi: 10.12144/zgmfskin202305355

• 病例报告 • 上一篇    下一篇

新冠疫苗接种后结节性类天疱疮一例

周芯宇1,2,李凡1,2,周兴丽1,2,李薇1,2,蒋献1,2   

  1. 1四川大学华西医院皮肤科，成都，610041；
    2四川大学华西医院皮肤病学研究室，成都，610041
  • 出版日期:2023-05-15 发布日期:2023-05-16

Pemphigoid nodularis following COVID-19 vaccination: a case report

ZHOU Xinyu1,2, LI Fan1,2, ZHOU Xingli1,2, LI Wei1,2, JIANG Xian1,2   

  1. 1 Department of Dermatology, West China Hospital of Sichuan University, Chengdu 610041, China;
    2 Dermatology Laboratory, West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2023-05-15 Published:2023-05-16

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摘要： 患者，男，68岁。躯干及四肢丘疹、结节伴瘙痒8个月。发病前3天患者注射第一剂新冠疫苗，注射第二剂后症状加重。结合组织病理、直接免疫荧光等检查，诊断为结节性类天疱疮。给予雷公藤多苷、米诺环素、硫唑嘌呤及强效糖皮质激素软膏等治疗3个月，病情逐渐好转。

关键词: 类天疱疮, 结节性, 大疱性, 新型冠状病毒疫苗

Abstract: A 68-year-old male presented with papules, nodules and pruritus on his trunk and limbs for eight months. He developed these rashes three days after the first dose of inactivated COVID-19 vaccine injection, and symptoms worsened after the second injection. Combined with pathology and direct immunofluorescence, the diagnosis of pemphigoid nodularis was made. The patient was treated with tripterygium wilfordii polyglycosides, minocycline, azathioprine and topical corticosteroids for 3 months, and his condition gradually improved.

Key words: pemphigoid, nodularis, bullous, COVID-19 vaccine