中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (5): 374-381.doi: 10.12144/zgmfskin202305374

• 综述 • 上一篇    下一篇

单克隆丙种球蛋白病相关的皮肤损害

张敏,游弋   

  1. 陆军军医大学第一附属医院皮肤科,重庆,400038
  • 出版日期:2023-05-15 发布日期:2023-05-17

Skin lesions associated with monoclonal gammopathy

ZHANG Min, YOU Yi   

  1. Department of Dermatology and Venereology, The First Affiliated Hospital, Army Medical University, Chongqing 400038, China
  • Online:2023-05-15 Published:2023-05-17

摘要: 单克隆丙种球蛋白病是由B淋巴细胞或浆细胞的克隆性增殖产生单克隆蛋白的一组疾病,可侵犯全身多个器官,如心脏、肝肾脏、神经、皮肤改变等,且均属于少见类型疾病,早期诊断与及时干预治疗有助于病情的控制以及预后。而皮肤受累表现因缺乏特异性,易被忽视,本文就该病的皮肤表现做一综述,为临床医生诊疗提供线索及思路。

关键词: 单克隆丙种球蛋白病, M蛋白, 皮肤

Abstract: Monoclonal gammopathy is a very rare disorder with the presence of excessive myeloma protein,caused by the aberrant clone of plasma cells or B cells. The disease has deleterious effects on the body,including the damage of liver, kidney or nerve systems and skin changes.The early diagnosis and timely treatment, thus, may contribute to the disease control and prognosis. However, the skin lesions in this disorder are lack of characteristics which can be easily neglected by doctors. Therefore, this paper reviews the skin manifestations of the disease to bring certain clues for clinicians to diagnose and treat.

Key words: monoclonal gammopathy, M-Proteinemia, skin