中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (4): 301-305.doi: 10.12144/zgmfskin202304301

• 综述 • 上一篇    下一篇

氨苯砜的非皮肤科应用及机制研究

涂小娇,赵晴,孙勇虎,张福仁   

  1. 山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2023-04-15 发布日期:2023-03-28

Non-dermatological therapies and mechanisms of depsone

TU Xiaojiao, ZHAO Qing, SUN Yonghu, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases ＆ Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University ＆ Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2023-04-15 Published:2023-03-28

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摘要： 氨苯砜（dapsone, DDS）被广泛应用于诸多感染性和炎症性皮肤病的治疗，随着对DDS作用机制的进一步了解，发现DDS还可以运用于治疗各系统损伤和退行性疾病甚至肿瘤疾病。本文就DDS的作用机制和DDS在非皮肤病应用做一综述。

关键词: 氨苯砜, 非皮肤病, 退行性疾病, 损伤, 肿瘤

Abstract: Dapsone(DDS) is a drug traditionally used in dermatological therapies due to its antimicrobial activity and anti-inflammatory effect. With further understanding of DDS mechanism, it has proven to be a safe and effective drug as a protector against cells damage, degenerative diseases and tumors. In this review, we discuss the mechanisms of action of DDS and Non-dermatological applications.

Key words: dapsone, non-dermatology, degenerative diseases, cells damage, tumors