中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (10): 752-755.doi: 10.12144/zgmfskin202310752

• 病例报告 • 上一篇    下一篇

原发性皮肤隐球菌病一例

王立程,陈东科,朱雄,林于金,钟山,何吕芬   

  1. 海南省三亚市人民医院中心实验室,海南三亚,572000
  • 出版日期:2023-10-15 发布日期:2023-10-11

Primary cutaneous cryptococcosis and literature review: a case report

WANG Licheng, CHEN Dongke, ZHU Xiong, LIN Yujin, ZHONG Shan, HE Lyufen   

  1. Department of Central Laboratory, People's Hospital of Sanya, Sanya 572000, China
  • Online:2023-10-15 Published:2023-10-11

摘要: 本文报道一例原发性皮肤隐球菌病,患者因右前臂红肿,皮肤破溃入院。脓液涂片见大量酵母样真菌孢子,菌体外周有荚膜包绕。真菌培养取乳白色菌落进行飞行时间质谱鉴定为新生隐球菌。抗感染治疗后行游离植皮手术,出院后继续口服氟康唑,60天后皮损基本愈合。

关键词: 隐球菌病, 皮肤, 感染, 诊断, 治疗

Abstract: We report a case of primary cutaneous cryptococcosis. The patient was admitted with red and swollen right forearm and skin ulceration. A large number of yeastlike fungal spores were found in the pus smear, and the cell was surrounded by a capsule. The milky white colonies were cultured and identified as Cryptococcus neoformans by time-of-flight mass spectrometry. After debridement and anti-infective treatment, free skin grafting was performed. Fluconazole was continued after discharge, and the skin lesions were basically healed after 60 days.

Key words: cryptococcosis, skin, infected, diagnosis, treatment