中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (12): 916-918.doi: 10.12144/zgmfskin202312916

• 病例报告 • 上一篇    下一篇

JAK1抑制剂治疗结节性痒疹一例

赵妍雯1,宋亚丽1，2   

  1. 1山东大学齐鲁医学院，山东济南，250012；2山东大学附属公共卫生临床中心，山东济南，250102
  • 出版日期:2023-12-15 发布日期:2023-11-22

Prurigo nodularis treated with upadacitini: a case report

ZHAO Yanwen1, SONG Yali1，2   

  1. 1 Cheeloo College of Medicine, Shandong University, Jinan 250012, China; 2 Public Health Clinical Center Affiliated to Shandong University, Jinan 250102, China
  • Online:2023-12-15 Published:2023-11-22

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摘要： 患者，女，26岁。四肢反复丘疹、结节伴瘙痒3年。曾口服环孢素、甲泼尼龙治疗，病情仍反复发作，加用JAK抑制剂乌帕替尼治疗后瘙痒迅速缓解，皮疹逐渐消退，随访4个月病情无反复。

关键词: 结节性痒疹, JAK抑制剂, 乌帕替尼, IL-31

Abstract:

A 26-year-old female presented with papules, nodules and pruritus for 3 years. After treated with oral cyclosporin and methylprednisolone, the condition still recurred. After treatment with the JAK inhibitor upatinibthe, the pruritus was controlled and the skin lesions gradually subsided. The condition was not repeated after 4 months follow-up. Dermatology examination showed bean-sized brown and flesh colored nodules distributed on the limbs.

Key words: prurigo nodularis, Janus kinase inhibitor, upadacitinib, IL-31