中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (11): 842-846.doi: 10.12144/zgmfskin202211842

• 综述 • 上一篇    

环状肉芽肿治疗新进展

白璐,朱才勇   

  1. 中国人民解放军陆军第八十集团军医院皮肤病科，潍坊，261031
  • 出版日期:2022-11-15 发布日期:2022-10-26

Update of treatment for annular granuloma

BAI Lu, ZHU Caiyong   

  1. Department of Dermatology, the Hospital of NO.80 Group Army of PLA, Weifang 261031, China
  • Online:2022-11-15 Published:2022-10-26

PDF (PC)

136

摘要： 环状肉芽肿（granuloma annulare，GA）是一种良性的自限性肉芽肿性疾病。TNF-α抑制剂和阿普斯特既可治疗GA，也可诱发GA。该病可与糖尿病、高脂血症等共存，与恶性肿瘤和甲状腺疾病等的关系存在争议。近年来，JAK抑制剂及度普利尤单抗等药物取得了良好疗效。本文从GA的诱因、共病、发病机制及治疗进展等方面进行综述，为该病的研究提供参考。

关键词: 环状肉芽肿, 诱因, JAK抑制剂, 度普利尤单抗

Abstract: Granuloma annulare (GA) is a benign self limiting non infectious granulomatous disease. TNF-α inhibitor and otezla can cure or induce GA, wihich can coexit with many diseases such as diebetes and hyperlipemia. There is controversy over the relationship between malignancy and thyroid diseases. In recent years, JAK inhibitors and dupilumab have achieved good curative effects. This paper comprehensively summarized the inducement, comorbidity, pathogenesis and treatment of GA, so as to make a reference for the research of GA in the future.

Key words: annular granuloma, inducement, JAK inhibitor, dupilumab