日光性荨麻疹,奥马珠单抗," /> 日光性荨麻疹,奥马珠单抗,"/> solar urticaria, omalizumab,"/> <span style="font-size:12px;">奥马珠单抗治疗儿童日光性荨麻疹一例并文献复习</span>

中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (2): 116-117.doi: 10.12144/zgmfskin202402116

• 临床研究 • 上一篇    下一篇

奥马珠单抗治疗儿童日光性荨麻疹一例并文献复习

曲芃1,2,杜东红1,2,杨宝琦1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；
    2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2024-02-15 发布日期:2024-01-31

Omalizumab in the treatment of childhood solar urticaria: a case report and literature review

QU Peng1,2, DU Donghong1,2, YANG Baoqi1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China;
    2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2024-02-15 Published:2024-01-31

PDF (PC)

130

摘要： 日光性荨麻疹传统治疗方案主要有抗组胺药物、光硬化、白三烯受体拮抗剂，然而有很多患者对传统治疗方案反应不佳。既往报道奥马珠单抗治疗儿童日光性荨麻疹有效，本文报道奥马珠单抗治疗儿童日光性荨麻疹一例,并进行文献复习。患者为一例3岁男性患儿，日晒后全身红斑、风团伴瘙痒1年。给予患者奥马珠单抗150 mg皮下注射，患者好转出院。随访22个月，患者目前维持奥马珠单抗治疗中，皮疹无复发。

关键词: 日光性荨麻疹')">">日光性荨麻疹, 奥马珠单抗

Abstract: The traditional treatment of solar urticaria mainly includes antihistamines, photosclerosis, leukotriene receptor antagonists, but many patients do not respond well to the traditional treatment. Some article have been reported that omazumab was effective in the treatment of children with solar urticaria. Herein, we report a  3-year-old child with solar urticaria treated with omalizumab, and review the related literature. The patient presented with erythema and wheal all over his body with pruritus after sun exposure for 1 year and was given 150mg omalizumab, then the lesions subsided. At a follow-up of 22 months, the patient was remained on omazumab treatment and the rash did not recur.

Key words: solar urticaria')">">solar urticaria, omalizumab