中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (7): 474-479.doi: 10.12144/zgmfskin202407474

• 论著 • 上一篇    下一篇

大疱性疥疮三例并文献复习

陈留鑫1,2,蔡艳霞1,刘雅芹1,2,杨艳平1,谢映霞1,2,邓诗音1,2,罗雅琪1,2   

  1. 1广东医科大学附属医院皮肤科，广东湛江，524000;2广东医科大学，广东湛江，524000
  • 出版日期:2024-07-15 发布日期:2024-06-11

Bullous scabies: 3 cases report and literature review

CHEN Liuxin1,2, CAI Yanxia1, LIU Yaqin1,2, YANG Yanping1, XIE Yingxia1,2, DENG Shiyin1,2, LUO Yaqi1,2   

  1. 1 Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, China; 2 Guangdong Medical University, Zhanjiang 524000, China
  • Online:2024-07-15 Published:2024-06-11

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摘要： 大疱性疥疮（bullous scabies，BS）是疥疮的一种罕见的临床表现，极易误诊。本文报道3例既往误诊的BS患者，并通过万方及PubMed学术数据库检索“大疱性疥疮”文献，检索到44篇文献，包括60例患者，总结分析该病的人口统计学信息、发病机制、临床表现、病理特点及治疗，发现BS好发于老年群体及男性患者，约1/3患者存在误诊史，3/4患者在接受糖皮质激素治疗后病情未见缓解或进一步进展。皮肤科医生应提高对该病的认识，并且治疗上应谨慎使用糖皮质激素。

关键词: 大疱性疥疮, 疥螨, 糖皮质激素, 大疱性类天疱疮

Abstract: Bullous scabies (BS) is a rare clinical manifestation of scabies that is easily misdiagnosed. In this paper, we report three patients with BS who were previously misdiagnosed and search the related literature in Wanfang and PubMed database, then analyze the demographic information, pathogenesis, clinical manifestations, pathological characteristics, and treatment of the disease. It is found that BS is more common in the elderly population and male patients, about one third of the patients had a history of misdiagnosis, and three quarters of the patients had no remission or further progression after receiving glucocorticoid treatment. It is suggested that dermatologists should improve their understanding and diagnosis of this disease and the treatment should be cautious with the use of glucocorticoids.

Key words: bullous scabies, sarcoptic mite, glucocorticoid, bullous pemphigoid