中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (12): 851-854.doi: 10.12144/zgmfskin202412851

• 论著 • 上一篇    下一篇

动脉瘤样纤维组织细胞瘤五例临床病理分析

张瑶,蔡海斌   

  1. 上海市复旦大学附属闵行医院皮肤科，上海，201199
  • 出版日期:2024-12-15 发布日期:2024-10-31

Clinicopathological analysis of five cases with aneurysmal fibrous histiocytomas

ZHANG Yao, CAI Haibin   

  1. Department of Dermatology, Minhang Hospital, Fudan University, Shanghai 201199, China
  • Online:2024-12-15 Published:2024-10-31

PDF (PC)

66

摘要： 动脉瘤样纤维组织细胞瘤是一种罕见的良性皮肤肿瘤，复发率高，正确的诊断和治疗对于预防复发至关重要。本文对2020年8月至2023年12月我院5例动脉瘤样纤维组织细胞瘤患者的临床和病理资料进行回顾性分析，其中男3例，女2例，2例皮损位于上肢，3例位于下肢，皮损直径大小0.6~1.2 cm。组织病理学表现除具有经典皮肤纤维瘤的组织学特征外，尚有不规则出血性裂隙和囊腔样结构。肿瘤细胞主要为组织细胞，无明显细胞异型性或核分裂象。免疫组化显示CD68阳性，Vimentin阳性，CD34阴性。5例患者均接受局部切除术，术后病理切缘阴性，无复发。

关键词: 动脉瘤样纤维组织细胞瘤, 临床特征, 组织病理学

Abstract: Aneurysmal fibrous histiocytomas is a rare benign skin tumor with a high recurrence rate, and correct diagnosis and treatment are essential to prevent recurrence. Herein, we retrospectively analyzed the clinical and pathological data of 5 patients with aneurysmal fibrous histiocytoma from August 2020 to December 2023. Among the 5 patients, 3 were males and 2 were females, the lesions were on the upper limbs in 2 cases and on the lower limbs in 3 patients. The diameter of the lesions were from 0.6 to 1.2 cm. In addition to the histological features of classical dermatofibroma, the tumor tissues had irregular hemorrhagic fissure, cystic structure, varying degrees of hemosiderin deposits and varying amounts of foamy cells, and touton giant cells in a few cases. Immunohistochemistry was positive for vimentin and CD68, while the vascular marker CD34 was negative. All the 5 patients underwent local resection without recurrence.

Key words: aneurysmal fibrous histiocytoma, clinical features, histopathology