中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (12): 875-877.doi: 10.12144/zgmfskin202412875

• 病例报告 • 上一篇    下一篇

单侧梅毒性角膜基质炎后角膜白斑合并神经梅毒一例

徐宇轩1,夏蔚2,徐雅婷1,李晶晶1,王千秋3,李姗姗1,戴军1,吴敏智1   

  1. 1苏州市第五人民医院皮肤科，江苏苏州，215000； 2苏州大学附属第一医院眼科，江苏苏州,215000； 3中国医学科学院北京大学医学院皮肤科，江苏南京，210042
  • 出版日期:2024-12-15 发布日期:2024-10-31

Corneal leucoma after unilateral syphilitic stromal keratitis complicated with neurosyphilis：a case report

XU Yuxuan1, XIA Wei2, XU Yating1, LI Jingjing1, WANG Qianqiu3, LI Shanshan1, DAI Jun1, WU Minzhi1   

  1. 1 Department of Dermatology, The Fifth People's Hospital of Suzhou, Suzhou 215000, China; 2 Ophthalmology Department, The First Affiliated Hospital of Soochow University, Suzhou 215000, China; 3 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Online:2024-12-15 Published:2024-10-31

PDF (PC)

57

摘要： 本文报道一例罕见的单侧梅毒性角膜基质炎后角膜白斑合并无症状神经梅毒。患者，女，30岁。右眼视物模糊10天，梅毒血清学检查阳性。脑脊液检查符合神经梅毒。给予患者青霉素钠驱梅治疗和甲泼尼龙预防吉海反应，治疗后视力恢复，角膜瘢痕形成，梅毒相关指标下降。本文提醒临床医生需加强对眼梅毒患者神经系统的全面评估，及时诊断和治疗。

关键词: 角膜基质炎, 角膜白斑, 眼梅毒, GWC系数, 神经梅毒

Abstract: We report a rare case of corneal leucoma after unilateral syphilitic stromal keratitis complicated with neurosyphilis. A 30-year-old female presented with blurry vision on the right eye for 10 days. Serologically positive for syphilis. Cerebrospinal fluid tests are consistent with neurosyphilis. The patient was treated with penicillin sodium and methylprednisolone to prevent Jarisch-Herxheimer reaction. After the treatment, the patient's vision recovered, corneal scarring formed, and syphilitic indicators decreased. This paper reminds clinicians to strengthen the comprehensive evaluation of the nervous system of patients with ocular syphilis, and timely diagnosis and treatment.

Key words: syphilitic stromal keratitis, corneal leucoma, ocular syphilis, Goldmann-Witmer coefficient, neurosyphilis