中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (8): 578-582.doi: 10.12144/zgmfskin202508578

• 论著 • 上一篇    下一篇

2020-2023年广州市男性婚检人群HBV、梅毒感染率及其影响因素分析

马骁,黄丽娟,梁月开,王宇   

  1. 广州市妇女儿童医疗中心增城院区妇保科，广东广州，511300
  • 出版日期:2025-08-15 发布日期:2025-07-31

Infection rate of HBV and syphilis in male premarital check-up population in Guangzhou from 2020 to 2023 and its influencing factors

MA Xiao, HUGNG Lijuan, LIANG Yuekai, WANG Yu   

  1. Department of Obstetrics and Gynecology, Zengcheng Campus of Guangzhou Women and Children's Medical Center, Guangzhou 511300, China
  • Online:2025-08-15 Published:2025-07-31

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摘要： 目的：分析2020-2023年广州市男性婚检人群中乙型肝炎病毒（HBV）和梅毒的感染率及影响因素。方法：选取2020年1月至2023年12月在我院进行婚检的22 596名男性作为研究对象。通过问卷调查收集其基本信息，包括年龄、文化程度、性行为史等，并检测其血清中的乙肝表面抗原（HBsAg）和梅毒螺旋体抗体。采用多因素Logistic回归分析法，探讨影响HBV和梅毒感染的相关因素。结果：广州市男性婚检人群的HBV感染率为1.50%（340/22 596），梅毒感染率为2.25%（508/22 596）。多因素Logistic回归分析显示，有乙肝疫苗接种史是HBV感染的保护因素（P＜0.05）；而文化程度较低（高中/中专及以下）、乙肝家族史、丙型肝炎史是HBV感染的危险因素（P＜0.05）。文化程度较低（高中/中专及以下）、与同性发生肛交性行为、性伴侣数量≥2人、有吸毒行为、最近1年患过性病、HIV抗体阳性、未坚持使用安全套是梅毒感染的危险因素（P＜0.05）。结论：广州市2020-2023年男性婚检人群HBV、梅毒感染率较高，且受多种因素的影响。

关键词: 男性, 婚检, 乙型肝炎病毒, 梅毒, 影响因素

Abstract: Objective: To analyze the infection rates and influencing factors of hepatitis B virus (HBV) and syphilis among male premarital check-ups in Guangzhou from 2020 to 2023. Methods: A total of 22 596 men who underwent premarital medical examinations in our hospital from January 2020 to December 2023 were selected as the research subjects. Their basic information, including age, educational level, and sexual behavior history were collected through questionnaire surveys, and hepatitis B surface antigen (HBsAg) and Treponema pallidum antibodies in their serum were detected. Multivariate Logistic regression analysis was used to analyze the related factors. Results: HBV infection rate was 1.50% (340/22 596) and syphilis infection rate was 2.25%(508/22 596) among male premarital check-up population in Guangzhou. Multiple Logistic regression analysis showed that hepatitis B vaccination history was a protective factor for HBV infection (P＜0.05). However, lower educational attainment (high school/technical secondary school and below), family history of hepatitis B or hepatitis C were risk factors for HBV infection (P＜0.05). Lower educational attainment (high school/technical secondary school and below), having anal sex with the same sex, having 2 or more sexual partners, admitting drug use, having a sexually transmitted diseases in the past 1 year, positive HIV antibody, failure to consistently use condoms were the risk factors for syphilis infection (P＜0.05). Conclusion: The infection rate of HBV and syphilis among male premarital check-ups in Guangzhou from 2020 to 2023 is high, and HBV and syphilis infection is affected by many factors.

Key words: male, premarital check-up, hepatitis B virus, syphilis, influencing factor