中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (10): 729-732.doi: 10.12144/zgmfskin202510729

• 临床研究 • 上一篇    下一篇

萎缩性花斑糠疹一例并文献复习

张子扬1，2,张雍1，2,暴芳芳1，2,田洪青1，2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022； 2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2025-10-15 发布日期:2025-09-28

Atrophying tinea versicolor: a case report and literature review

ZHANG Ziyang1,2, ZHANG Yong1,2, BAO Fangfang1,2, TIAN Hongqing1,2   

  1. 1 Dermatology Hospital of Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2025-10-15 Published:2025-09-28

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摘要： 萎缩性花斑糠疹是花斑糠疹的罕见亚型，以特征性皮肤萎缩伴色素异常为主要表现。本文报道一例患者，男，39岁，病程8年，真菌检查阳性，组织病理示表皮萎缩符合萎缩性花斑糠疹。予伊曲康唑胶囊100 mg口服，外用复方苯甲酸酊与硝酸舍他康唑乳膏，1个月后症状消退，局部皮损痊愈。停药1个月后随访，皮损无复发。结合文献复习32例患者，本病好发于中青年（中位年龄35岁），男女比例均衡，21.9%与长期外用糖皮质激素相关。抗真菌治疗有效率62.5%，但37.5%遗留持续性萎缩。

关键词: 萎缩性花斑糠疹

Abstract: Atrophying tinea versicolor (ATV) is a rare variant of tinea versicolor characterized by cutaneous atrophy with dyspigmentation. We report a 39-year-old male with 8-year history of ATV, initially misdiagnosed as common tinea versicolor, confirmed by pathology and fungal examination . The patient received oral itraconazole (100mg daily) combined with topical compound benzoic acid tincture and sertaconazole nitrate 2% cream. Complete resolution was achieved after one month of treatment, with no recurrence observed at one-month follow-up. A literature review of 32 patients showed that this disease predominantly affects young and middle-aged individuals (median age 35 years), with an equal gender ratio. 21.9% of cases were associated with long-term topical glucocorticoid use. The effective rate of antifungal treatment was 62.5%, while 37.5% of patients had persistent atrophy as a sequela.

Key words: atrophying tinea versicolor