中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (5): 313-314.doi: 10.12144/zgmfskin202605313

• 新发与再发感染性皮肤病 • 上一篇    下一篇

海分枝杆菌感染一例

武欣萌,董正邦   

  1. 东南大学附属中大医院,江苏南京,210009
  • 出版日期:2026-05-15 发布日期:2026-05-11

Mycobacterium marinum infection: a case report

WU Xinmeng, DONG Zhengbang   

  1. Zhongda Hospital Southeast University, Nanjing 210009, China
  • Online:2026-05-15 Published:2026-05-11

摘要: 患者,女,24岁,左手背结节2月余。曾在外院行细菌培养阴性,诊断为“疣”,给予冷冻治疗,皮损逐渐加重。后就诊于我院,皮肤科查体见左手背三个暗红色结节,蚕豆至鸽蛋大小,质软,皮温正常,轻度压痛,行皮肤组织DNA下一代测序技术(NGS)提示海分枝杆菌感染。予利福平、莫西沙星治疗2个月,皮损较前明显好转。

关键词: 海分枝杆菌, 游泳池肉芽肿, 冷冻治疗

Abstract: A 24-year-old female presented with nodules on the dorsum of her left hand for more than 2 months. Bacterial culture performed at an outside hospital was negative, and she was diagnosed with “verruca” and received cryotherapy, but the skin lesions gradually worsened. She was subsequently admitted to our hospital. Dermatological examination showed three dark red nodules on the dorsum of the left hand, ranging in size from broad bean to pigeon egg, soft in texture, normal skin temperature, and mild tenderness. Bacterial culture in another hospital was negative. Next-generation DNA sequencing (NGS) of skin tissue in our hospital indicated Mycobacterium marinum infection. The patient was treated with rifampicin and moxifloxacin for 2 months, and the condition improved significantly compared with before.

Key words: Mycobacterium marinum, swimming pool granuloma, cryotherapy