中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (2): 80-82.

• 论著 • 上一篇    下一篇

银屑病患者血清尿酸水平与动脉粥样硬化的相关性研究

陈国梁,徐金华   

  1. 复旦大学附属华山医院皮肤科，上海20040
  • 出版日期:2018-02-15 发布日期:2018-12-06
  • 通讯作者: 徐金华，E-mail:13816586496@163.com

Correlation of serum uric acid levels and atherosclerosis in the patients with psoriasis

CHEN Guoliang, XU Jinhua.   

  1. Department of Dermatology，Fudan University Huashan Hospital , Shanghai 200040, China
  • Online:2018-02-15 Published:2018-12-06
  • Contact: XU Jinhua, E-mail:13816586496@163.com

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摘要： 目的：明确银屑病患者血清尿酸水平与血脂、亚临床动脉粥样硬化的关系。方法: 回顾性分析286例银屑病患者和235名正常对照的血清尿酸、血脂水平,颈动脉内膜中层厚度（IMT）及颈动脉斑块情况。结果：银屑病患者高尿酸血症达38.1%，高于对照组的17.9%。高尿酸银屑病患者的甘油三酯水平、IMT值及颈动脉斑块的阳性率高于无高尿酸银屑病患者。结论: 银屑病患者高尿酸血症可能与血脂水平和颈动脉斑块的发生相关。

关键词: 银屑病, 高尿酸血症, 动脉粥样硬化

Abstract: Objective: To determine the correlation between serum uric acid levels and atherosclerosis in the patients with psoriasis. Methods: The levels of serum uric acid, blood lipids, carotid intima-media thickness (IMT) and carotid plaque in 286 patients and 235 healthy controls were analyzed retrospectively. Results: The detection rate of hyperuricemia in the patients with psoriasis was 38.1%, which was higher than that in the controls (17.9%). The level of blood lipids, IMT and the positivity rate of carotid plaque in the patients with hyperuricemia were higher than those in the patients without hyperuricemia. Conclusion: Hyperuricemia in the patients with psoriasis may be associated with high level of serum lipid and atherosclerosis.

Key words: psoriasis, hyperuricemia, atherosclerosis