中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (6): 439-441.doi: 10.12144/zgmfskin202506439

• 病例报告 • 上一篇    下一篇

儿童隆突性皮肤纤维肉瘤一例

余平子1,李伟泽1,万苗坚2,曾义燕3   

  1. 1贵州中医药大学第二附属医院，贵州贵阳，550001；2中山大学附属第三医院，广东广州，510600；3贵州中医药大学第一附属医院，贵州贵阳，550001
  • 出版日期:2025-06-15 发布日期:2025-05-23

Dermatofibrosarcoma protuberans in a child: a case report

YU Pingzi1, LI Weize1, WAN Miaojian2, ZENG Yiyan3   

  1. 1 Department of Dermatology， The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine， Guiyang 550001， China； 2 The Third Affiliated Hospital,Sun Yat-Sen University, Guangzhou 510600, China; 3 Department of Dermatology， The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine， Guiyang 550001， China
  • Online:2025-06-15 Published:2025-05-23

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摘要： 儿童隆突性皮肤纤维肉瘤罕见，易漏诊、误诊。本文报道一例出生时即出现皮损的病例。 患儿，男，2 岁。左臀部蚕豆大小淡紫色斑块，逐渐增大、增多2年。皮损组织病理示：肿瘤位于真皮及皮下，由梭形或短梭形细胞构成，弥漫或席纹状排列，细胞有异型性，可见核分裂。免疫组化示：CD34（+），CD68、CD31、CK、S100、EmA均阴性，Ki-67(约2%+）。诊断：隆突性皮肤纤维肉瘤。治疗：MMS显微描记手术，术后随访无复发。

关键词: 皮肤纤维肉瘤, 隆突性, 儿童

Abstract: Dermatofibrosarcoma protuberans in children is rare and often leads to missed diagnosis and misdiagnosis. This paper presents a case of skin lesions present at birth. A 2-year-old boy presented with a light purple patch, about the size of a broad bean, on the left buttock. Over the past two years,both the size and the number of these patches have gradually increased. Histopathological examination showed the tumor was located in the dermis and subcutaneous tissue. It was composed of spindle or short spindle cells, arranged diffusely or in a storiform pattern, the cells were atypical and nuclear division was seen. Immunohistochemical staining showed CD34 was positive, CD68, CD31, CK, S100 and EmA, and CD1a were negative. Ki-67 proliferation index was 2%.The diagnosis of dermatofibrosarcoma protuberans was made. The patient was treated with Mohs micrographic surger, and there was no recurrence during the one-year follow-up.

Key words: dermatofibrosarcoma, protuberans, child